Twenty years is a very long time — for a relationship or a TV sequence like Gray’s Anatomy. Simply while you suppose there’s nothing extra to do, shock!
Followers proceed to tune into Gray’s each season for the newest medical circumstances, relationship drama, and sturdy storytelling.
We do not get as a lot Meredith as of late, however there’s nonetheless sufficient to fulfill viewers, together with the connection mishaps together with her new love curiosity.
Whereas the present would not have the identical pizzazz and character compatibility because it did within the early years, there’s loads of relationship messiness to entice followers.
However regardless of how nice — or dangerous — issues get at GSM, some relationships have occurred within the final 20 years that followers will always remember. And a few by no means received the ending they deserve.
Here’s a record of our favourite on-screen Gray’s Anatomy ‘ships of all time.
Meredith Gray and Derek Shepherd
The chemistry between Meredith Gray and Derek Shepherd hooked viewers from the primary glimpse and nonetheless captivates 20 years later.
A love like theirs by no means dies, even when one (Derek) does. Their relationship went by the worst of ups and downs, like assembly Derek’s spouse (ex).
No different couple has captured that air of eternal love, of being there for one another it doesn’t matter what.
Derek might not be with Meredith in individual anymore, however we will nonetheless really feel their love years after Derek’s soul left this mortal airplane.
Meredith Gray and Nick Marsh
Followers cherished the union between Nick and Meredith from the beginning. Meredith was lastly opening her coronary heart once more years after Derek’s loss of life.
What began as long-distance turned a severe ‘ship when Nick joined the employees at Gray Sloan. Whereas Meredith left GSM for a job in Minnesota.
In Season 20, followers adore seeing Nick taking part in the attentive dad or mum to the children again in Minnesota whereas Mer is again in Seattle at GSM.
Critically, can they ever be in the identical place concurrently?
Derek Shepherd and Addison Montgomery Shepherd
We will not point out Derek’s former relationship with out together with them on this record. As a result of the 2 docs made an unbelievable pairing to start with.
Earlier than Addison had an affair with Derek’s greatest buddy Mark. It is her infidelity that pushed Derek to Gray Sloan (Seattle Grace Hospital) and into the arms of Meredith.
Whereas Derek and Addison have been nonetheless married on the time, it was in title solely.
Viewers had a cut up response on whether or not Derek ought to have labored more durable to maintain his marriage with Addison going or finish the ‘ship to concentrate on what was growing between him and Meredith.
As soon as a cheater and all that. The Mer-team received as Derek lastly selected a path.
Addison Montgomery and Mark Sloan
We fell in love with the horny womanizer Mark Sloan from our first assembly, regardless of being a scoundrel for his affair with Addison.
We had much less constructive emotions for Addison, the dishonest spouse.
Regardless of their relationship beginning by infidelity, we instantly rooted for them.
If Addie was with Mark, Derek was free to pursue Meredith.
It did not take lengthy to study that Mark wasn’t simply Dr. McSteamy, an attractive face and hard-toned physique. He was additionally an excellent, proficient physician and a pleasant man with robust relationship potentialities.
We virtually felt sorry for his love-sick emotions. He gave up his life within the metropolis to observe Addi to Seattle.
Regardless of his sacrifices, their relationship withered into nothingness. Nevertheless, everybody stayed good pals, so there was gentle on the finish of the tunnel.
Mark Sloan and Callie Torres
Mark’s character made him an ideal candidate to be pals with females like Addison and Callie Torres.
He and Callie began off as a random hookup.
They usually continued to have a sexual association with out the messy feelings of a relationship. Many followers hoped they’d turn into extra.
Alas, friendship is all that was there, regardless of having a daughter collectively in later seasons. Their friendship helped Callie notice her bisexuality, getting her on observe to satisfy the 2 nice loves of her life — each females.
Mark Sloan and Lexie Gray
Poor Mark went by the wringer by way of relationships. It appeared like he could not catch a break on discovering the precise lady.
First Addison, then Callie.
Issues appeared to vary when he met the candy and younger Lexie Gray. Sparks flew, as did the tensions and warnings. Their union was forbidden, which made it all of the extra thrilling.
We noticed a distinct aspect to Mark, however his need for a secret relationship wasn’t truthful to Lexi, even when it was for good causes — like conserving his greatest buddy from discovering out he was sleeping along with his sister-in-law.
Whereas the eagerness was there, the muse wasn’t. Mark wished youngsters. Lexie did not.
Regardless of splitting up, they stayed in love proper up till their deaths after the airplane crash in Season 8 Episode 24.
Callie Torres and George O’Malley
George was a nerdy physician, so nobody was extra shocked than him when the new Callie confirmed curiosity. However she was, as have been we.
However whereas Callie appeared to be all in, George was extra reluctant to commit. He proposed on a whim, and so they received married in Vegas.
However the marriage was a brief one. Callie left George after discovering out about his one-night stand and true emotions for Izzie.
His loss of life hit Callie onerous, leading to her going again to Sloan, paving the best way for her to have Mark’s child and uncover her twin sexuality.
George O’Malley and Izzie Stevens
The connection between George and Izzie Stevens lasted longer in nuance than it did in actuality. They’d a powerful, supportive love, but it surely was extra of a greatest buddy who was all the time there for you.
First, George was in love with Izzie however saved quiet. Then when he was married, Izzie determined she cherished him too.
After a one-night stand, their relationship tried to take off. Most of us followers weren’t right here for it.
Fortunately, it faltered on the beginning line. They unanimously agreed it wasn’t the precise time. Sadly, they by no means noticed what may have been earlier than George died heroically.
Izzie Stevens and Denny Duquette
Regardless of the rule towards docs courting their sufferers, Izzie Stevens fell for Denny Duquette, a affected person in want of a coronary heart transplant.
When it seemed like Denny would die earlier than getting a brand new organ, Izzie broke the legislation and her oath to push him up the transplant record.
Though he received a brand new coronary heart and proposed to Izzie, he died of a stroke shortly after she accepted.
His loss of life continued to have an effect on Izzie by future ‘ships. His ghost identified her mind tumor.
Callie Torres and Arizona Robbins
The connection between Callie and Arizona was one among battle and drama and plenty of on-again, off-again.
As Arizona courted Callie, she concurrently seduced the viewers.
The couple went by the ringer, experiencing job adjustments, a disagreement on youngsters, and a airplane crash that killed a number of GSM docs.
Followers knew we have been witnessing a love that might outlast something. Besides we have been improper.
The couple had a number of main fights that ultimately led to a nasty custody battle over Sophia, the daughter Callie shared with Mark.
Most followers hated the best way their love story ended so brutally merciless. Callie left Gray Sloan to be together with her new girlfriend, Penny, in New York. Arizona adopted later to be near her daughter.
Followers discovered they reunited off-screen just a few years later. Arizona’s look on Gray’s Anatomy Season 20 Episode 4 left followers disenchanted that we did not study the place the couple stands.
Callie Torez and Penny Blake
We weren’t certain what to make of Penny Blake when she joined Gray’s. And as soon as she turned the physician that killed Derek, we had our minds made up.
So, followers had blended emotions as soon as she and Callie received severe. Whereas we wished our lady to be glad, we weren’t certain it ought to be with Blake. The connection did not keep on display screen so long as others but it surely had main affect.
When Blake received a job throughout the nation, Callie adopted. Sadly, not earlier than followers went by plenty of drama, just like the custody battle.
Gray’s followers ended up saying goodbye to a different of their favourite docs. Later, it is talked about that the couple broke up just a few years after the transfer.
Alex Karev and Lexie Gray
Meredith is not the one Gray with relationship issues. Lexie additionally had fairly a time discovering real love.
Like a number of different Gray Sloan employees, she had a quick fling with fellow physician Alex Karev. Followers noticed the writing on the wall from the beginning.
Poor Lexi could be doomed for heartache if she fell for Alex, since he was in love with another person. (See a pattern?)
Fortunately, she by no means absolutely invested within the relationship and wasn’t devastated when it fizzled out.
Alex Karev and Izzie Stevens
Izzie and Alex have been pals earlier than they turned lovers. Given their horrible observe file for relationships — like falling for his or her sufferers — followers had blended emotions when the 2 began having chemistry.
Alone, each docs have been a large number. However they introduced out one of the best in one another.
The romance allowed the playboy Alex to redeem himself as he proposed to Izzie regardless of considering she was going to die from most cancers.
As an alternative of the marriage for Meredith and Derek, we watched Alex and Izzie take part holy matrimony.
Though Izzie survived her analysis, their marriage didn’t. Followers had blended emotions about Alex’s resolution to finish issues after Izzie left however returned for a second likelihood.
Alex Karev and Jo Wilson
Izzie had been good for Alex in some ways, together with serving to him mature into a fantastic physician.
So when sparks flew between him and Jo Wilson, followers knew he was lastly prepared for a severe relationship.
Alex and Jo have been two peas in a pod regardless of all of the drama of their relationship stemming from the previous. After they lastly overcame their hurdles, we have been certain to see a fortunately ever after.
Issues have been good till they weren’t. With out warning, Alex left sooner or later to go to his mother. Or so we thought.
Then all of a sudden, he is AWOL, no telephone calls, no correspondence. Full ghosting.
Turned out he discovered his child mamma, Izzie, and selected to stick with her over his present spouse. Delivering the information and divorce papers within the mail? Harsh transfer, Doc!
Jo Wilson and Atticus Lincoln
After two failed marriages, Jo was hesitant to be with anybody else, particularly after adopting daughter Luna.
However who may resist falling for horny surgeon Hyperlink.
Hyperlink and Jo’s relationship goes again to their pre-doctor days, after they labored collectively as meals servers.
At first, they have been simply actually shut pals, however followers noticed the chemistry.
The chums turned lovers after Hyperlink’s failed relationship with Amelia gave him a son. Whereas elevating their youngsters as single dad and mom, emotions grew right into a romantic love.
Season 20 has the 2 in couple mode, and issues appear to be going properly up to now into the shortened season.
Jackson Avery and April Kepner
Jackson got here onto the scene because the boss’s son and April because the religious Christian.
After Jackson took April’s virginity, most followers anticipated them to remain collectively.
However after a lot pointless forwards and backwards, followers received over the redundancy and began to hope for one thing else.
We noticed plenty of repeated storylines — April virtually married the improper man, she left the nation, she got here again prepared to choose up the place they left off.
Regardless of marriage and shared youngsters, Jackson was unwilling to place within the work, and their union fizzled out.
The couple divorced however later rekindled their ‘ship off-screen when April and their daughter adopted Jackson to Boston.
Jackson Avery and Lexie Gray
Gray’s Anatomy has been a revolving door of shared companions. Followers have seen loads of meant-to-be hookups and simply as many WTF are you considering ‘ships.
After Jackson and April cut up up and Lexie dumped Mark, issues began to warmth up for the 2 newly single docs.
The connection between Lexie and Jackson was primal and purely bodily, as each folks have been nonetheless in love with their “one.”
It was clear from the start that they have been utilizing one another as an escape.
So it did not shock anybody when Jackson dumped Lexie as a result of nonetheless being in love with Mark.
Cristina Yang and Preston Burke
Cristina was everybody’s favourite sensible, egotistical surgeon, and Burke was the proper mentor. Their coupling cut up followers.
The connection appeared inappropriate for a lot of as a result of Burke was Cristina’s boss.
Though there have been challenges, such because the distinction in job title and spiritual beliefs, the couple stayed collectively till their marriage ceremony day.
On what was to be one of the best day of their lives, Cristina skilled the worst when Preston left her on their marriage ceremony day.
Cristina Yang and Owen Hunt
Owen Hunt got here to Gray Sloan in a flurry of motion and physician brilliance.
It is no surprise his distinctive method of medical therapy caught the attention of Yang.
Their courtship was messy and appeared like it might finish a number of occasions, however they ended up married as an alternative.
Though there was lots that ought to have saved them aside.
A number of elements labored, like nails in a coffin, to lastly finish their marriage. They initially divorced for the lawsuit after the airplane crash.
However Cristina left to take a job in Switzerland and absolutely ended their relationship when she realized Owen wished youngsters. She did not.
Amelia Shepherd and Owen Hunt
From our first introduction, Amelia was a large number. Though Derek’s sister, followers didn’t see a lot household resemblance.
Each docs had a tough previous, with loads of demons nonetheless haunting them. Hunt had PTSD from his time at conflict.
Amelia was a drug addict with a mind tumor that induced irrational conduct.
Distress loves firm, so nobody felt stunned when the couple tied the knot. Simply as the wedding started, the couple argued about having youngsters, which led to an amicable divorce.
Followers watched in horror as they determined to strive their relationship once more after the mind tumor was gone.
However earlier than we needed to get on board with spherical 2, they skilled a closing blowout that led to the tip of their coupling.
Amelia Shepherd and Atticus Hyperlink
After the failed ‘ship between Amelia and Owen, there was the opportunity of Amelia with Hyperlink.
Followers have been in love with the gorgeous boy surgeon who gave Amelia all the eye and understanding she did not get with Owen.
He even pretended to be her former husband throughout a household dinner, so Amelia would not must admit to her divorce.
He went to bat for her and followers weren’t the one ones to understand his assist.
The couple began as pals, grew into lovers, had a toddler collectively, and cut up up. However regardless of their division, the couple are glorious at co-parenting.
Owen Hunt and Teddy Altman
Teddy and Owen return pre-hospital to after they labored collectively abroad as Military surgeons.
Regardless of having emotions for one another within the desert, they begin with a platonic relationship as soon as Teddy involves Seattle Grace.
The couple lastly received their likelihood collectively after Owen went by a number of failed relationships, together with with Cristina and Amelia.
Issues have been rocky from day 1 as Teddy struggled to be the backup. It wasn’t till she received pregnant that she was able to strive with Owen.
Who was nonetheless with Amelia.
After the start of their daughter, Owen lastly proposed to Teddy, who was in one other relationship on the identical time.
The couple are nonetheless married — though there’s usually drama — in Season 20.
Miranda Bailey and Ben Warren
Miranda’s massive character and brilliance made everybody fall in love together with her, together with then-anesthesiologist Ben Warren — now a firefighter at Station 19.
After Bailey’s catastrophe of a wedding to her first husband Tuck, followers swooned over the extreme wooing Ben did to seize her consideration.
Every little thing concerning the man appeared good, which solely appeared to work towards him as Bailey resisted his advances.
Followers are thrilled to see that her disinterest did not final lengthy.
Their love story is the epitome of what we expect an ideal marriage ought to be, even years later when most different relationships have fallen to the wayside.
Richard Webber and Catherine Fox
The early seasons of Gray’s Anatomy revealed the historical past between Richard and Meredith’s mom, efficiently laying the muse for all the sequence.
After the emotional ordeal of Richard’s first marriage, followers have been glad to see him get a second likelihood at love.
Nobody anticipated extra heartache within the works as his new love, Catherine, received sick too.
The person significantly cannot catch a break! It is no surprise he struggles with alcohol.
As of Season 20, followers are glad to see the wedding nonetheless going robust and maintain out hope that Catherine’s present well being prognosis continues to remain constructive.
Levi Schmitt and Nico Kim
Levi made fairly the impression as a surgical resident. Since his nerdy fumbling as a primary 12 months, he is turn into fairly the physician. Even when his love life hasn’t labored out as properly.
Followers cheered in delight when Levi lastly discovered somebody to assist him discover his sexuality. Nico was the proper first, however followers by no means anticipated it to be Levi’s solely.
Sadly, their relationship did not final, however nobody ever forgets their first. Particularly when it is as life-changing as realizing you are homosexual.
Many followers hoped that Nico would return and the couple may begin once more.
Nobody anticipated to see Nico re-appear in Season 20 Episode 3, fortunately married and with a child on the best way.
It broke poor Levi’s coronary heart, however followers hope it was the closure he wanted to lastly transfer on and discover his real love.
Maggie Pierce and Winston Ndugu
Maggie’s arrival at GSM induced fairly a stir since Meredith was unaware she had one other sister.
And Richard was simply as shocked to seek out out he had a daughter.
Maggie had just a few relationships earlier than Winston, together with Andrew DeLucas and a quick dalliance with Jackson Avery (whose mother was married to her dad).
Originally of their relationship, Maggie and Winston lived lengthy distance. She lived in Seattle, and he was in Boston.
After COVID, Winston relocated to Seattle to work at Gray Sloan, and the couple received engaged.
Issues appeared to maneuver quick for them and the followers, leaving a lot to be desired. When the issues began, we barely had time to regulate to the wedding.
Sadly, followers mentioned goodbye to Maggie and the union in Season 19. The divorce papers delivered to Winston in Season 20 gave us a much-needed, if awkward, decision.
Simone Griffith and Lucas Adams
Simone and Lucas are two of the most recent residents to hitch the ranks of Gray’s. Followers have paralleled their love story and that of Derek and Mer.
It is no shock, given Lucas’s DNA. He’s Derek’s nephew, in any case. He has greatness in his genes.
Lucas has been in love with Simone since they met.
And Simone was engaged to another person. The marriage virtually occurred, however Simone known as it off on the final minute.
Nobody, together with the couple, appears to know the place they stand. If issues can work out, we would have our subsequent real love story.
What do you consider this record of the best relationships on Gray’s Anatomy? Is there a relationship we did not embrace that you simply like?
Remember to remark along with your decide for one of the best couple.
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Sara Trimble is a employees author for TV Fanatic. You’ll be able to observe her on X.
